Gastrointestinal histological injury in pigs subjected to triple stent interposition in the thoracoabdominal aorta

Gastrointestinal histological injury in pigs subjected to triple stent interposition in the thoracoabdominal aorta

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ABSTRACT Purpose: To evaluate gastrointestinal histological injury in pigs subjected to triple stent interposition versus a control group, hypothesizing no significant injury increase with triple stents.Methods: A prospective study with 15 pigs divided into a control group (G0, n = 5) undergoing arteriography only, and a triple stent group (G3, n = 10) undergoing arteriography and three stent implantations in the thoracoabdominal aorta.After an eight-day observation, arteriography, euthanasia, and en bloc gastrointestinal harvesting were wilds of eldraine prerelease guide performed.

Lesions were graded using the Park/Chiu classification, and serum markers were analyzed pre- and post-procedure.Results: Arteriography confirmed mesenteric artery patency in all animals.Histological analysis showed ischemic lesions in 88.

9% of G3, mainly in the colon (89%), compared to 60% in G0, primarily in the colon (60%) and stomach (40%).Most G3 lesions were grade 1, while G0 had higher-grade lesions.Serum markers showed no significant intergroup differences.

Conclusion: Triple stent interposition did not significantly increase gastrointestinal tonic shower cap injury, indicating its safety for maintaining gastrointestinal perfusion in this model.